Take the Quiz
Affiliate Disclosure: This page contains affiliate links. We may earn a commission when you sign up — at no additional cost to you. Read our full disclosure.
Note on laboratory work, September 17, 2026. Where this page describes NexLife’s Care360 program as including baseline labs, that description comes from this site’s May 2026 editorial review. On a first-party read of nexlife.us on September 17, 2026 no public page (plan pages, FAQ, homepage, microdose pages) states that laboratory review or bloodwork is included — the FAQ describes Care 360 “metabolic health tracking” — so the labs point is recorded as under re-verification and should be confirmed at intake. NexLife’s plan pages name three fulfilling pharmacies (Absolute Pharmacy (Lutz, FL), Premium Compounding (Decatur, AL) and Boudreaux’s New Drug Store (Lake Charles, LA)). Prices and every other statement on this page are unaffected.
Weight Loss · GLP-1 (daily)

Liraglutide

Liraglutide is a daily-injection GLP-1 receptor agonist with a 13-hour half-life. The original FDA-approved GLP-1 for weight management (Saxenda, 2014); now largely superseded by weekly semaglutide and tirzepatide.

Category: Weight Loss / GLP-1 Last updated 2026-05-25
Liraglutide at a glance

Liraglutide is a daily-injection GLP-1 receptor agonist with a 13-hour half-life. The original FDA-approved GLP-1 for weight management (Saxenda, 2014); now largely superseded by weekly semaglutide and tirzepatide. Mechanism: GLP-1 receptor agonist. Typical route: Subcutaneous injection. FDA status: FDA-approved as Victoza (2010, T2D) and Saxenda (2014, weight management). Generic liraglutide became available in 2024. Now the third-line GLP-1 choice after weekly semaglutide and tirzepatide for mo

Drug classGLP-1 receptor agonist
Half-life~13 hours (daily dosing)
RouteSubcutaneous injection
Typical maintenance3.0 mg/day (weight)
FDA statusApproved (Saxenda, Victoza)
Compounded availabilityYes (some pharmacies)

Mechanism of action

Liraglutide activates the GLP-1 receptor, slowing gastric emptying, increasing satiety, and improving glucose-dependent insulin secretion. Its shorter half-life requires daily subcutaneous dosing rather than weekly.

Dosing reference

Standard titration: 0.6 mg/day for one week, increased by 0.6 mg/day each week to a maintenance dose of 3.0 mg/day (Saxenda) for weight management or 1.8 mg/day (Victoza) for type 2 diabetes.

Dosing information is provided for educational reference and is not medical advice. Patients should not initiate or modify any peptide regimen without consulting a licensed clinician. See our medical disclaimer.

FDA status & regulatory framework

FDA-approved as Victoza (2010, T2D) and Saxenda (2014, weight management). Generic liraglutide became available in 2024. Now the third-line GLP-1 choice after weekly semaglutide and tirzepatide for most patients.

Editor's Pick · #1 of 10
NexLife compounded semaglutide 5 mg/mL injection vial — 2.5 mL, prescription only, for subcutaneous use only
NexLife — Compounded Semaglutide
★★★★★ 4.8
Trustpilot aggregate · verify on Trustpilot →
  • ✨ Editor's Pick · 94/100
  • 💊 Compounded semaglutide + tirzepatide
  • 👨‍⚕️ MD/DO-supervised
  • 🏥 503A & 503B pharmacies
  • 🩺 Provider oversight included
  • 📍 All 50 states
  • ✓ LegitScript-certified
  • 💰 Flat-rate, dose-independent
  • 🔁 Care360 + 1:1 fitness coaching
  • 🍽️ Personalized nutrition plan
  • 💳 Klarna & Affirm accepted
$119/ month*

*12-month plan · save $240/yr · flat rate across full 0.25–2.4 mg titration. $125 (6-mo, save $84) · $132 (3-mo, save $21) · $139 (monthly).

Includes: medication, all MD/DO visits, messaging (lab review under re-verification), personalized nutrition plan (GLP-1 focused), 1:1 fitness call with certified wellness coach, and medical guidance.

Klarna & Affirm financing accepted at checkout (FAQ).

Visit NexLife →

Or call (949) 818-8000

Trade-offs to know

Compounded only — no brand-name Wegovy® / Ozempic® / Rybelsus®. Cash-pay with HSA/FSA only — no in-network insurance billing. Compounded medications are not FDA-approved (applies to all compounded GLP-1 providers). Eligibility, prescription, and outcomes are determined by the licensed prescriber and are not guaranteed.

Editor's Pick · #1 of 10 · Tirzepatide
NexLife compounded tirzepatide 20 mg/mL injection vial — 3 mL, prescription only, for subcutaneous use only
NexLife — Compounded Tirzepatide
★★★★★ 4.7
Trustpilot aggregate · verify on Trustpilot →
  • ✨ Editor's Pick · 94/100
  • 💊 Compounded semaglutide + tirzepatide
  • 👨‍⚕️ MD/DO-supervised
  • 🏥 503A & 503B pharmacies
  • 🩺 Provider oversight included
  • 📍 All 50 states
  • ✓ LegitScript-certified
  • 💰 Flat-rate, dose-independent
  • 🔁 Care360 coaching
  • 📱 Apple Health / Google Fit sync
$139/ month*

*12-month plan · flat rate across full 2.5–15 mg titration. $149 (6-mo) · $159 (3-mo) · $169 (month-to-month).

Includes: medication, all visits, messaging, lab review, and Care360 coaching.

Compounded tirzepatide via 503A & 503B pharmacies.

Visit NexLife →

Or call (949) 818-8000

Trade-offs to know

Compounded only — no brand-name Wegovy® / Zepbound®. Cash-pay with HSA/FSA only — no in-network insurance billing. Compounded medications are not FDA-approved (applies to all compounded GLP-1 providers). Eligibility, prescription, and outcomes are determined by the licensed prescriber and are not guaranteed.

U.S. telehealth providers that work with Liraglutide

EDITOR'S TOP PICK · #1 of 5
96/100v3.0 six-pillar rubric

Starting at $119/mo. NexLife is one of the providers covered in our editorial directory that dispenses or coordinates Liraglutide.

Read review →
#2 of 5
88/100v3.0 six-pillar rubric

Starting at $160/mo. Defy Medical is one of the providers covered in our editorial directory that dispenses or coordinates Liraglutide.

Read review →
#3 of 5
80/100v3.0 six-pillar rubric

Starting at $149/mo. Hone Health is one of the providers covered in our editorial directory that dispenses or coordinates Liraglutide.

Read review →
#4 of 5
78/100v3.0 six-pillar rubric

Starting at $149/mo. Eden Health is one of the providers covered in our editorial directory that dispenses or coordinates Liraglutide.

Read review →
#5 of 5
76/100v3.0 six-pillar rubric

Starting at $149/mo. Henry Meds is one of the providers covered in our editorial directory that dispenses or coordinates Liraglutide.

Read review →

Related weight loss / glp-1 peptides

Browse the full Weight Loss / GLP-1 category →

Frequently asked questions about Liraglutide

Why use liraglutide if weekly options exist?

Liraglutide may be preferred when generic pricing makes it cheaper than newer agents, when a patient cannot tolerate side effects of semaglutide or tirzepatide, or when daily dosing flexibility is desired.

How does liraglutide compare to semaglutide for weight loss?

In trials, liraglutide produced about 5-8% body weight loss at 56 weeks, compared with 14.9% for semaglutide at 68 weeks. Most patients now start with semaglutide or tirzepatide unless there is a specific reason to choose liraglutide.

References

  1. Pi-Sunyer X, Astrup A, Fujioka K, et al. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management (SCALE Obesity and Prediabetes). N Engl J Med. 2015;373(1):11-22. PMID: 26132939
  2. Marso SP, Daniels GH, Brown-Frandsen K, et al. Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes (LEADER). N Engl J Med. 2016;375(4):311-322. PMID: 27295427
  3. U.S. Food and Drug Administration. FDA approves weight-management drug Saxenda. FDA Press Release. December 23, 2014. View source

Sources are peer-reviewed where available. PubMed (PMID) links resolve to NCBI's PubMed database. FDA links resolve to the U.S. Food and Drug Administration. Citations were last verified 2026-05-11.

Lead Medical Researcher
Dr. Sam Saberian
Doctor of Pharmacy; leads protocol research, peptide pharmacology, and provider evaluation.
Medical Reviewer
Alen A. Schwartz, MD
Board-certified physician; reviews clinical accuracy of every published page.
Edited by
Julliana Edwards
Editorial standards, factual accuracy, and corrections workflow.