Dose range
2.5 → 15 mg/wk
Route
Subcutaneous injection, once weekly
Indication(s)
Chronic weight management; OSA in obesity

Titration schedule

StepDoseDurationNotes
12.5 mgWeeks 1-4
25 mgWeeks 5-8
37.5 mgWeeks 9-12
410 mgWeeks 13-16
512.5 mgWeeks 17-20
615 mgWeek 21+Max
Get compounded tirzepatide from NexLife

NexLife offers flat-rate compounded tirzepatide at $139/mo on the 12-month plan — same monthly price across the full titration ladder. MD/DO oversight, three pharmacies named on its plan pages, Care360 coaching included.

Check NexLife Tirzepatide → Full review

Important notes

  • This FDA-approved drug dosing chart is intended as a reference for clinicians and patients reviewing protocols, not a substitute for individualized prescriber guidance.
  • FDA-approved label dosing.
  • Compounded versions, where applicable, must be prepared by a licensed 503A or 503B compounding pharmacy. FDA has warned compounders that used salt forms (semaglutide sodium and semaglutide acetate), which are not the active ingredient in any approved drug.

References

  1. Zepbound (brand tirzepatide) prescribing information / clinical literature.
  2. FDA, bulk drug substances used in compounding under section 503A (interim categories), accessed October 2026.
  3. USP <797>: Pharmaceutical Compounding — Sterile Preparations.