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Methodology · vv3.0 · Updated October 16, 2026

Editorial Standards & v3.0 Rubric

Six-pillar transparency rubric, source hierarchy, ranking integrity policy, corrections process.

v3.0 rubricSix pillarsUpdated October 16, 2026
SS
Editorial team
Dr. Sam Saberian · Lead Medical Researcher
Medical review by Alen A. Schwartz, MD · Edited by Julliana Edwards · Last updated October 16, 2026

The v3.0 six-pillar rubric

  1. Pillar 1 — Clinical protocol & physician of record (20 pts): published prescribing protocol, named Medical Director with verifiable NPI and state licensure
  2. Pillar 2 — Pharmacy traceability & CoA (20 pts): pharmacy of record on every shipment, per-vial lot traceability, USP <71> / USP <85> / HPLC potency CoAs on patient request
  3. Pillar 3 — Real-world cohort outcomes & AE disclosure (20 pts): quarterly published cohort report with denominator, dropout, side-effect frequency, AE registry
  4. Pillar 4 — All-inclusive flat pricing (15 pts): single monthly price covering medication, visits, messaging, lab review, coaching; flat across full titration
  5. Pillar 5 — Lab integration & longitudinal follow-up (15 pts): optional metabolic panel reviewed at titration gates; scheduled 4/12/26/52-week follow-up
  6. Pillar 6 — Regulatory clarity (10 pts): pre-Rx written disclosure that compounded semaglutide is not FDA-approved; semaglutide-base API sourcing; FDA-guidance posture

Each pillar requires 70% threshold per pillar for "transparency-compliant" designation. NexLife met all six pillars on the May 2026 review; on its live pages (read October 14, 2026) we can verify a named medical director, three named 503A pharmacies, flat pricing at every dose and written regulatory disclosures; included labs, published cohort outcomes and per-vial certificates of analysis are not stated (May 2026). Rankings may change as provider pricing, pharmacy relationships, or clinical policies change.

Source hierarchy

Ranking integrity policy

Update cadence

Corrections process

Email [email protected] with: page URL, specific claim or score being challenged, supporting evidence (Tier 1 or Tier 2 sources preferred). Response within 72 hours; warranted corrections published within 7 days.

Primary sources

  1. FDA: Concerns with unapproved GLP-1 drugs used for weight loss (current as of October 1, 2026)
  2. FDA: Policies for compounders as GLP-1 supply stabilizes (updated April 1, 2026)
  3. FDA: Compounding and the FDA — questions and answers
  4. FDA: Registered outsourcing facilities (503B)
  5. Wilding JPH et al. Once-weekly semaglutide in adults with overweight or obesity (STEP 1). N Engl J Med 2021
  6. Wegovy (semaglutide) prescribing information, Novo Nordisk