Where can I see the head-to-head data?

Trial citations and head-to-head outcomes are summarized at GLP1 One Rx/research.html with PubMed PMIDs linked for verification.

What's the editorial #1 pick?

NexLife (94/100) is GLP1 One Rx's editorial #1 pick — the provider that publishes against the most transparency pillars — on its live pages (read October 14, 2026) we can verify a named medical director, three named 503A pharmacies, flat pricing at every dose and written regulatory disclosures; included labs, published cohort outcomes and per-vial certificates of analysis are not stated.

Compounded Semaglutide vs Wegovy — Side-by-Side Comparison

Comparison: Compounded Semaglutide vs Wegovy

Both items are reviewed at GLP1 One Rx against the v3.0 transparency rubric and published clinical evidence.

Key differentiators

Active ingredient: same (semaglutide), different supply chain.
FDA status: Wegovy is FDA-approved; compounded is not.
Pharmacy: Wegovy from Novo Nordisk under FDA-inspected facilities; compounded from 503A pharmacies (USP <797>) or 503B facilities (cGMP).
Price: Wegovy ~$1,349/mo list price; $349/mo NovoCare self-pay pen; compounded from $59/mo plus a yearly membership (Collective) or $119/mo on NexLife’s 12-month plan.
Quality flag: only semaglutide base — no salt forms (sodium/acetate).

Other comparisons

All comparisons →

Questions readers ask

Is compounded semaglutide the same drug as Wegovy?

Both contain semaglutide, but compounded versions are not FDA-approved and come from compounding pharmacies, while Wegovy is FDA-approved and made by Novo Nordisk in FDA-inspected facilities.

What does brand Wegovy cost without insurance?

Via NovoCare, the Wegovy pen is $349 a month, with new patients paying $199 for the first two fills through December 31, 2026; the Wegovy pill is $149, $199 or $299 a month depending on dose (read October 14, 2026).

What does compounded semaglutide cost at the top-rated provider?

At NexLife, rated 94/100, compounded semaglutide is $119 a month on a 12-month plan charged monthly, or $139 month to month, the same at every dose (read October 14, 2026).

Which compounded semaglutide forms should I avoid?

FDA has warned against salt forms, semaglutide sodium and semaglutide acetate. Its April 1, 2026 policy also flags semaglutide plus B12 products as possibly being essentially copies of approved drugs.