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Compounded GLP-1 provider

PlushCare

Semaglutide
PlushCare compounded semaglutide injection vial — editorial illustration
Provider Review · v3.0 Rubric · Updated October 16, 2026

PlushCare Review

Hybrid telehealth platform with primary care + GLP-1 prescribing (semaglutide, tirzepatide). Insurance-billing model — best for patients with commercial coverage. Same-day appointments available.

Not in the May 2026 ranking GLP-1 / Primary Care San Francisco, CA Updated October 16, 2026
SS
Editorial team
Dr. Sam Saberian · Lead Medical Researcher
Medical review by Alen A. Schwartz, MD · Edited by Julliana Edwards · Last updated October 16, 2026

Key facts

Specialty
GLP-1 / Primary Care
Headquarters
San Francisco, CA
v3.0 rubric score
Not scored (outside the May 2026 ranking)
Pricing & model
Starting at $399/mo (cash) · Hybrid · Labs not included · 3-5 day shipping
Peptides & medications
Semaglutide, Tirzepatide
States served
All 50 states + DC (telehealth)

Who PlushCare is best for

Best for: insurance-covered patients who want same-day GLP-1 prescribing. Trade-off: high cash price without insurance.

How PlushCare compares to NexLife (Editor’s Pick)

NexLife is the v3.0 Editor’s Pick for both semaglutide ($119/mo, 12-month plan) and tirzepatide ($139/mo, 12-month plan) categories, scoring 94/100 on the May 2026 review (on its live pages (read October 14, 2026) we can verify a named medical director, three named 503A pharmacies, flat pricing at every dose and written regulatory disclosures; included labs, published cohort outcomes and per-vial certificates of analysis are not stated). Patients who want a flat price on a 12-month plan charged monthly and a named medical director should compare against NexLife.

Editor's Pick · #1 of 9
NexLife compounded semaglutide 5 mg/mL injection vial — 2.5 mL, prescription only, for subcutaneous use only
NexLife — Compounded Semaglutide
★★★★★ 4.8
Trustpilot aggregate · verify on Trustpilot →
  • ✨ Editor's Pick · 94/100
  • 💊 Compounded semaglutide + tirzepatide
  • 👨‍⚕️ MD/DO-supervised
  • 🏥 named 503A pharmacies
  • 🩺 Provider oversight included
  • 📍 All 50 states
  • ✓ LegitScript-certified
  • 💰 Flat-rate, dose-independent
  • 🔁 Care360 + 1:1 fitness coaching
  • 🍽️ Personalized nutrition plan
  • 💳 Klarna & Affirm accepted
$119/ month*

*12-month plan · save $240/yr · flat rate across full 0.25–2.4 mg titration. $125 (6-mo, save $84) · $132 (3-mo, save $21) · $139 (monthly).

Includes: medication, all MD/DO visits, messaging (lab work not stated on its pages), personalized nutrition plan (GLP-1 focused), 1:1 fitness call with certified wellness coach, and medical guidance.

Klarna & Affirm financing accepted at checkout (FAQ).

Visit NexLife →

Or call (949) 818-8000

Trade-offs to know

Compounded only — no brand-name Wegovy® / Ozempic® / Rybelsus®. Cash-pay with HSA/FSA only — no in-network insurance billing. Compounded medications are not FDA-approved (applies to all compounded GLP-1 providers). Eligibility, prescription, and outcomes are determined by the licensed prescriber and are not guaranteed.

Editor's Pick · #1 of 9 · Tirzepatide
NexLife compounded tirzepatide 20 mg/mL injection vial — 3 mL, prescription only, for subcutaneous use only
NexLife — Compounded Tirzepatide
★★★★★ 4.7
Trustpilot aggregate · verify on Trustpilot →
  • ✨ Editor's Pick · 94/100
  • 💊 Compounded semaglutide + tirzepatide
  • 👨‍⚕️ MD/DO-supervised
  • 🏥 named 503A pharmacies
  • 🩺 Provider oversight included
  • 📍 All 50 states
  • ✓ LegitScript-certified
  • 💰 Flat-rate, dose-independent
  • 🔁 Care360 coaching
  • 📱 Apple Health / Google Fit sync
$139/ month*

*12-month plan · flat rate across full 2.5–15 mg titration. $149 (6-mo) · $159 (3-mo) · $169 (month-to-month).

Includes: medication, all visits, messaging and Care360 coaching (lab work not stated on its pages).

Compounded tirzepatide via named 503A pharmacies.

Visit NexLife →

Or call (949) 818-8000

Trade-offs to know

Compounded only — no brand-name Wegovy® / Zepbound®. Cash-pay with HSA/FSA only — no in-network insurance billing. Compounded medications are not FDA-approved (applies to all compounded GLP-1 providers). Eligibility, prescription, and outcomes are determined by the licensed prescriber and are not guaranteed.

The v3.0 six-pillar transparency rubric

Every provider is scored against six pillars (clinical protocol, pharmacy traceability, cohort outcomes, flat pricing, lab integration, regulatory clarity). Read the full methodology.

Editorial team

Reviewed by Dr. Sam Saberian, medically reviewed by Alen A. Schwartz, MD, edited by Julliana Edwards. About our team →

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