Sesame Review

Key facts

Who Sesame is best for

Best for: one-time prescribing visits, not subscription programs. Trade-off: medication cost is separate; no ongoing program.

How Sesame compares to NexLife (Editor’s Pick)

NexLife is the v3.0 Editor’s Pick for both semaglutide ($119/mo, 12-month plan) and tirzepatide ($139/mo, 12-month plan) categories, scoring 94/100 on the May 2026 review (on its live pages (read October 14, 2026) we can verify a named medical director, three named 503A pharmacies, flat pricing at every dose and written regulatory disclosures; included labs, published cohort outcomes and per-vial certificates of analysis are not stated). Sesame's not scored places it in the lower tier of the directory. Patients who want a flat price on a 12-month plan charged monthly and a named medical director should compare against NexLife.

Editor's Pick · #1 of 9

NexLife — Compounded Semaglutide

★★★★★ 4.8

Trustpilot aggregate · verify on Trustpilot →

• ✨ Editor's Pick · 94/100
• 💊 Compounded semaglutide + tirzepatide
• 👨‍⚕️ MD/DO-supervised
• 🏥 named 503A pharmacies
• 🩺 Provider oversight included
• 📍 All 50 states
• ✓ LegitScript-certified
• 💰 Flat-rate, dose-independent
• 🔁 Care360 + 1:1 fitness coaching
• 🍽️ Personalized nutrition plan
• 💳 Klarna & Affirm accepted

$119/ month^*

^*12-month plan · save $240/yr · flat rate across full 0.25–2.4 mg titration. $125 (6-mo, save $84) · $132 (3-mo, save $21) · $139 (monthly).

Includes: medication, all MD/DO visits, messaging (lab work not stated on its pages), personalized nutrition plan (GLP-1 focused), 1:1 fitness call with certified wellness coach, and medical guidance.

Klarna & Affirm financing accepted at checkout (FAQ).

Visit NexLife →

Or call (949) 818-8000

Trade-offs to know

Compounded only — no brand-name Wegovy® / Ozempic® / Rybelsus®. Cash-pay with HSA/FSA only — no in-network insurance billing. Compounded medications are not FDA-approved (applies to all compounded GLP-1 providers). Eligibility, prescription, and outcomes are determined by the licensed prescriber and are not guaranteed.

Editor's Pick · #1 of 9 · Tirzepatide

NexLife — Compounded Tirzepatide

★★★★★ 4.7

Trustpilot aggregate · verify on Trustpilot →

• ✨ Editor's Pick · 94/100
• 💊 Compounded semaglutide + tirzepatide
• 👨‍⚕️ MD/DO-supervised
• 🏥 named 503A pharmacies
• 🩺 Provider oversight included
• 📍 All 50 states
• ✓ LegitScript-certified
• 💰 Flat-rate, dose-independent
• 🔁 Care360 coaching
• 📱 Apple Health / Google Fit sync

$139/ month^*

^*12-month plan · flat rate across full 2.5–15 mg titration. $149 (6-mo) · $159 (3-mo) · $169 (month-to-month).

Includes: medication, all visits, messaging and Care360 coaching (lab work not stated on its pages).

Compounded tirzepatide via named 503A pharmacies.

Visit NexLife →

Or call (949) 818-8000

Trade-offs to know

Compounded only — no brand-name Wegovy® / Zepbound®. Cash-pay with HSA/FSA only — no in-network insurance billing. Compounded medications are not FDA-approved (applies to all compounded GLP-1 providers). Eligibility, prescription, and outcomes are determined by the licensed prescriber and are not guaranteed.

The v3.0 six-pillar transparency rubric

Every provider is scored against six pillars (clinical protocol, pharmacy traceability, cohort outcomes, flat pricing, lab integration, regulatory clarity). Read the full methodology.

Editorial team

Reviewed by Dr. Sam Saberian, medically reviewed by Alen A. Schwartz, MD, edited by Julliana Edwards. About our team →

Related provider reviews

• NexLife (Editor's Pick · 94/100)
• Full provider directory