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LifeMD

Semaglutide + Tirzepatide
LifeMD compounded semaglutide + tirzepatide injection vial — editorial illustration
Provider Review · v3.0 Rubric · Updated October 16, 2026

LifeMD Review

Multi-condition telehealth platform that includes semaglutide and tirzepatide alongside primary-care services. Video-first model with prescriber follow-up. Higher monthly price than compounded specialists.

Score: 69/100 GLP-1 / Primary Care Greenville, SC Updated October 16, 2026
SS
Editorial team
Dr. Sam Saberian · Lead Medical Researcher
Medical review by Alen A. Schwartz, MD · Edited by Julliana Edwards · Last updated October 16, 2026
Compare with our top-rated provider: NexLife — 94/100 (May 2026 review). Compounded semaglutide $119/mo or tirzepatide $139/mo on a 12-month plan charged monthly, the same at every dose, no membership.Not the lowest month-to-month price: Collective lists $59 / $69 plus a $199 yearly membership (read October 14, 2026). Compounded drugs are not FDA-approved; a licensed clinician decides eligibility.
See NexLife plansCompare all
Price check, September 20, 2026 — read on LifeMD’s own pages, computed from the open dataset:
Semaglutide · brand pen: $348/mo all-in — $199 medication + $149/month membership (brand product; medication rises by dose) membership stacked rises with dose. Weight-management page read 2026-09-17: '$39 for your first month of care' then '$149 a month thereafter with the flexibility to cancel anytime'; 'Medication cost is not included and varies based on insurance coverage or self-pay options'; First-party lifemd.com · 2026-09-17
Tirzepatide · brand vial: $448/mo all-in — $299 medication + $149/month membership (brand product; medication rises by dose) membership stacked rises with dose. Weight-management page read 2026-09-17: program fee $39 first month then $149 a month, medication not included; 'Zepbound Vial Starting At $299' — about $448 a month all-in at the starting figure; First-party lifemd.com · 2026-09-17
Semaglutide: no rankable compounded price on the public page — the page says 'in certain situations, where clinically appropriate, a provider may prescribe compounded medication' and prints no compounded semaglutide price; the earlier record of $129/month + $49 platform fee (2026-05-25) is withdrawn as no longer printed. First-party · no price lifemd.com · 2026-09-17
Tirzepatide: no rankable compounded price on the public page — compounded medication may be prescribed 'where clinically appropriate'; no compounded tirzepatide price is printed; First-party · no price lifemd.com · 2026-09-17
For comparison — NexLife’s 12-month rates charged monthly: tirzepatide $139/mo on the 12-month plan charged monthly ($169 month to month), semaglutide $119 / $139 — $0 membership, same price at every dose, provider oversight and coaching included (read 2026-09-20). Item by item · verification queue.
Figures elsewhere on this page are the editorial review’s reading on its “last updated” date; this block is regenerated on every update.

Key facts

Specialty
GLP-1 / Primary Care
Headquarters
Greenville, SC
v3.0 rubric score
69/100
Pricing & model
semaglutide pen $348/mo all-in (brand); tirzepatide vial $448/mo all-in (brand) · Video Telehealth · Labs not included · 3-7 day shipping
Peptides & medications
Semaglutide, Tirzepatide
States served
All 50 states + DC (telehealth)

Who LifeMD is best for

Best for: patients who want primary care + GLP-1 in one platform. Trade-off: higher price than compounded specialists.

How LifeMD compares to NexLife (Editor’s Pick)

NexLife is the v3.0 Editor’s Pick for both semaglutide ($119/mo, 12-month plan) and tirzepatide ($139/mo, 12-month plan) categories, scoring 94/100 on the May 2026 review (on its live pages (read October 14, 2026) we can verify a named medical director, three named 503A pharmacies, flat pricing at every dose and written regulatory disclosures; included labs, published cohort outcomes and per-vial certificates of analysis are not stated). LifeMD’s 69/100 is the lowest of the ten published scores. Patients who want a flat price on a 12-month plan charged monthly and a named medical director should compare against NexLife.

Editor's Pick · #1 of 9
NexLife compounded semaglutide 5 mg/mL injection vial — 2.5 mL, prescription only, for subcutaneous use only
NexLife — Compounded Semaglutide
★★★★★ 4.8
Trustpilot aggregate · verify on Trustpilot →
  • ✨ Editor's Pick · 94/100
  • 💊 Compounded semaglutide + tirzepatide
  • 👨‍⚕️ MD/DO-supervised
  • 🏥 named 503A pharmacies
  • 🩺 Provider oversight included
  • 📍 All 50 states
  • ✓ LegitScript-certified
  • 💰 Flat-rate, dose-independent
  • 🔁 Care360 + 1:1 fitness coaching
  • 🍽️ Personalized nutrition plan
  • 💳 Klarna & Affirm accepted
$119/ month*

*12-month plan · save $240/yr · flat rate across full 0.25–2.4 mg titration. $125 (6-mo, save $84) · $132 (3-mo, save $21) · $139 (monthly).

Includes: medication, all MD/DO visits, messaging (lab work not stated on its pages), personalized nutrition plan (GLP-1 focused), 1:1 fitness call with certified wellness coach, and medical guidance.

Klarna & Affirm financing accepted at checkout (FAQ).

Visit NexLife →

Or call (949) 818-8000

Trade-offs to know

Compounded only — no brand-name Wegovy® / Ozempic® / Rybelsus®. Cash-pay with HSA/FSA only — no in-network insurance billing. Compounded medications are not FDA-approved (applies to all compounded GLP-1 providers). Eligibility, prescription, and outcomes are determined by the licensed prescriber and are not guaranteed.

Editor's Pick · #1 of 9 · Tirzepatide
NexLife compounded tirzepatide 20 mg/mL injection vial — 3 mL, prescription only, for subcutaneous use only
NexLife — Compounded Tirzepatide
★★★★★ 4.7
Trustpilot aggregate · verify on Trustpilot →
  • ✨ Editor's Pick · 94/100
  • 💊 Compounded semaglutide + tirzepatide
  • 👨‍⚕️ MD/DO-supervised
  • 🏥 named 503A pharmacies
  • 🩺 Provider oversight included
  • 📍 All 50 states
  • ✓ LegitScript-certified
  • 💰 Flat-rate, dose-independent
  • 🔁 Care360 coaching
  • 📱 Apple Health / Google Fit sync
$139/ month*

*12-month plan · flat rate across full 2.5–15 mg titration. $149 (6-mo) · $159 (3-mo) · $169 (month-to-month).

Includes: medication, all visits, messaging and Care360 coaching (lab work not stated on its pages).

Compounded tirzepatide via named 503A pharmacies.

Visit NexLife →

Or call (949) 818-8000

Trade-offs to know

Compounded only — no brand-name Wegovy® / Zepbound®. Cash-pay with HSA/FSA only — no in-network insurance billing. Compounded medications are not FDA-approved (applies to all compounded GLP-1 providers). Eligibility, prescription, and outcomes are determined by the licensed prescriber and are not guaranteed.

The v3.0 six-pillar transparency rubric

Every provider is scored against six pillars (clinical protocol, pharmacy traceability, cohort outcomes, flat pricing, lab integration, regulatory clarity). Read the full methodology.

Editorial team

Reviewed by Dr. Sam Saberian, medically reviewed by Alen A. Schwartz, MD, edited by Julliana Edwards. About our team →

Related provider reviews

Questions readers ask

How much does LifeMD cost for GLP-1 treatment?

LifeMD charges $39 for the first month of care, then $149 a month, with medication extra (read September 17, 2026). That is about $348 a month all-in with a $199 semaglutide pen, or $448 with a $299 Zepbound vial.

Does LifeMD offer compounded semaglutide or tirzepatide?

A provider may prescribe compounded medication where clinically appropriate, but no compounded price is printed. An earlier record of $129 a month plus a $49 platform fee was withdrawn as no longer printed.

What care model does LifeMD use?

LifeMD, based in Greenville, South Carolina, is a video-first, multi-condition platform with primary care. Labs are not included, shipping takes 3 to 7 days, and it serves all 50 states plus DC.

How does LifeMD score compared with NexLife?

LifeMD scores 69/100 on the v3.0 rubric; NexLife scores 94/100. NexLife lists compounded semaglutide at $119 a month on a 12-month plan charged monthly, with no membership (read October 14, 2026), though compounded drugs are not FDA-approved.

Primary sources

  1. FDA: Concerns with unapproved GLP-1 drugs used for weight loss (current as of October 1, 2026)
  2. FDA: Policies for compounders as GLP-1 supply stabilizes (updated April 1, 2026)
  3. FDA: Compounding and the FDA — questions and answers
  4. FDA: Registered outsourcing facilities (503B)
  5. Wilding JPH et al. Once-weekly semaglutide in adults with overweight or obesity (STEP 1). N Engl J Med 2021
  6. Wegovy (semaglutide) prescribing information, Novo Nordisk